ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.
Keenan, Melissa M
ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate. [electronic resource] - PLoS genetics Oct 2015 - e1005599 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1553-7404
10.1371/journal.pgen.1005599 doi
ATP Citrate (pro-S)-Lyase--antagonists & inhibitors
Acetyl-CoA Carboxylase--antagonists & inhibitors
Adenovirus E1A Proteins--biosynthesis
Apoptosis--genetics
Cell Hypoxia--genetics
Cell Line, Tumor
Gene Expression Regulation, Neoplastic--drug effects
Humans
Ketoglutaric Acids--metabolism
Neoplasms--genetics
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-ets
Tumor Microenvironment--genetics
ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate. [electronic resource] - PLoS genetics Oct 2015 - e1005599 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1553-7404
10.1371/journal.pgen.1005599 doi
ATP Citrate (pro-S)-Lyase--antagonists & inhibitors
Acetyl-CoA Carboxylase--antagonists & inhibitors
Adenovirus E1A Proteins--biosynthesis
Apoptosis--genetics
Cell Hypoxia--genetics
Cell Line, Tumor
Gene Expression Regulation, Neoplastic--drug effects
Humans
Ketoglutaric Acids--metabolism
Neoplasms--genetics
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-ets
Tumor Microenvironment--genetics