Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization.

Courtaut, Flavie

Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization. [electronic resource] - Oncotarget Sep 2015 - 26651-62 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.5791 doi


Caspase 1--metabolism
Cell Line
Cell Line, Tumor
Colon--cytology
Colonic Neoplasms--metabolism
Cytoplasm--metabolism
Enzyme Activation
Epithelial Cells--metabolism
Gene Expression Regulation, Neoplastic
HCT116 Cells
Humans
Hydrocarbons, Fluorinated--chemistry
Intestinal Mucosa--metabolism
Ligands
Liver X Receptors
Orphan Nuclear Receptors--metabolism
Retinoid X Receptor alpha--metabolism
Sulfonamides--chemistry