Correlation of In Vivo Versus In Vitro Benchmark Doses (BMDs) Derived From Micronucleus Test Data: A Proof of Concept Study.

Soeteman-Hernández, Lya G

Correlation of In Vivo Versus In Vitro Benchmark Doses (BMDs) Derived From Micronucleus Test Data: A Proof of Concept Study. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Dec 2015 - 355-67 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1096-0929

10.1093/toxsci/kfv189 doi


Animal Testing Alternatives--standards
Animals
Benchmarking--standards
Cell Line
Dose-Response Relationship, Drug
Humans
Lymphocytes--drug effects
Micronuclei, Chromosome-Defective--chemically induced
Micronucleus Tests--standards
Models, Biological
Reproducibility of Results
Risk Assessment