Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells.

Chen, Xi

Lack of intracellular replication of M. tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells. [electronic resource] - Oncotarget Oct 2015 - 32456-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.5932 doi


Animals
Brain--blood supply
Capillary Permeability
Cell Line
Endothelial Cells--metabolism
Lysosomal-Associated Membrane Protein 2--metabolism
Lysosomes--metabolism
Mice
Microbial Viability
Microscopy, Confocal
Microscopy, Electron, Transmission
Microvessels--metabolism
Mycobacterium bovis--growth & development
Mycobacterium tuberculosis--growth & development
Time Factors
Virulence
rab GTP-Binding Proteins--metabolism
rab5 GTP-Binding Proteins--metabolism
rab7 GTP-Binding Proteins