p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells.

Cappadone, C

p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells. [electronic resource] - Biochemical and biophysical research communications Nov 2015 - 348-53 p. digital

Publication Type: Journal Article

1090-2104

10.1016/j.bbrc.2015.09.154 doi


Alkaline Phosphatase--genetics
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin-Dependent Kinase Inhibitor p21--genetics
Gene Expression
Humans
Indoles--pharmacology
Osteoblasts--drug effects
RNA, Small Interfering--genetics
Thiazoles--pharmacology
Tumor Suppressor Protein p53--antagonists & inhibitors