A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.

Papayannidis, C

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. [electronic resource] - Blood cancer journal Sep 2015 - e350 p. digital

Publication Type: Clinical Trial, Phase I; Letter; Research Support, Non-U.S. Gov't

2044-5385

10.1038/bcj.2015.80 doi


Adolescent
Adult
Antineoplastic Agents--pharmacokinetics
Female
High-Throughput Nucleotide Sequencing
Humans
Male
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Receptor, Notch1--genetics
Tetrahydronaphthalenes--therapeutic use
Valine--analogs & derivatives
Young Adult