Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma.

Capaldo, Brian J

Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma. [electronic resource] - PloS one 2015 - e0138210 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0138210 doi


Amino Acid Substitution
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
Humans
Indoles--pharmacology
MAP Kinase Signaling System--drug effects
Melanoma--drug therapy
Mutation, Missense
Proto-Oncogene Protein c-ets-2--genetics
Proto-Oncogene Proteins B-raf--genetics
Sulfonamides--pharmacology