Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway.
Zhang, Wenjuan
Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway. [electronic resource] - Journal of applied toxicology : JAT 07 2016 - 914-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1099-1263
10.1002/jat.3223 doi
Cell Line
Cell Proliferation--drug effects
Cell Survival--drug effects
Flame Retardants--toxicity
Hep G2 Cells
Humans
Liver--cytology
Organophosphates--toxicity
Oxidation-Reduction
Phosphatidylinositol 3-Kinases--genetics
Plasticizers--toxicity
Proto-Oncogene Proteins c-akt--genetics
RNA, Messenger--genetics
Reactive Oxygen Species--metabolism
Signal Transduction
Sirtuin 1--genetics
TOR Serine-Threonine Kinases--genetics
Up-Regulation
Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway. [electronic resource] - Journal of applied toxicology : JAT 07 2016 - 914-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1099-1263
10.1002/jat.3223 doi
Cell Line
Cell Proliferation--drug effects
Cell Survival--drug effects
Flame Retardants--toxicity
Hep G2 Cells
Humans
Liver--cytology
Organophosphates--toxicity
Oxidation-Reduction
Phosphatidylinositol 3-Kinases--genetics
Plasticizers--toxicity
Proto-Oncogene Proteins c-akt--genetics
RNA, Messenger--genetics
Reactive Oxygen Species--metabolism
Signal Transduction
Sirtuin 1--genetics
TOR Serine-Threonine Kinases--genetics
Up-Regulation