Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
Peter, B
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth. [electronic resource] - Leukemia Feb 2016 - 464-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5551
10.1038/leu.2015.242 doi
Adult
Aged
Basophils--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Female
Histamine Release--drug effects
Humans
Male
Mast Cells--drug effects
Mastocytosis--drug therapy
Middle Aged
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-kit--metabolism
Staurosporine--analogs & derivatives
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth. [electronic resource] - Leukemia Feb 2016 - 464-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5551
10.1038/leu.2015.242 doi
Adult
Aged
Basophils--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Female
Histamine Release--drug effects
Humans
Male
Mast Cells--drug effects
Mastocytosis--drug therapy
Middle Aged
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-kit--metabolism
Staurosporine--analogs & derivatives