The Effect of a Selective Inhibitor of Phosphodiesterase-9 on Oxidative Stress, Inflammation and Cytotoxicity in Neutrophils from Patients with Sickle Cell Anaemia.
Barbosa, Maritza Cavalcante
The Effect of a Selective Inhibitor of Phosphodiesterase-9 on Oxidative Stress, Inflammation and Cytotoxicity in Neutrophils from Patients with Sickle Cell Anaemia. [electronic resource] - Basic & clinical pharmacology & toxicology Apr 2016 - 271-8 p. digital
Publication Type: Journal Article
1742-7843
10.1111/bcpt.12487 doi
Adult
Anemia, Sickle Cell--blood
Biomarkers--metabolism
Cell Survival--drug effects
Female
Humans
Inflammation
Male
Neutrophils--drug effects
Nitric Oxide--metabolism
Oxidative Stress--drug effects
Peroxidase--immunology
Phosphodiesterase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Tumor Necrosis Factor-alpha--immunology
The Effect of a Selective Inhibitor of Phosphodiesterase-9 on Oxidative Stress, Inflammation and Cytotoxicity in Neutrophils from Patients with Sickle Cell Anaemia. [electronic resource] - Basic & clinical pharmacology & toxicology Apr 2016 - 271-8 p. digital
Publication Type: Journal Article
1742-7843
10.1111/bcpt.12487 doi
Adult
Anemia, Sickle Cell--blood
Biomarkers--metabolism
Cell Survival--drug effects
Female
Humans
Inflammation
Male
Neutrophils--drug effects
Nitric Oxide--metabolism
Oxidative Stress--drug effects
Peroxidase--immunology
Phosphodiesterase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Tumor Necrosis Factor-alpha--immunology