The Effect of a Selective Inhibitor of Phosphodiesterase-9 on Oxidative Stress, Inflammation and Cytotoxicity in Neutrophils from Patients with Sickle Cell Anaemia.

Barbosa, Maritza Cavalcante

The Effect of a Selective Inhibitor of Phosphodiesterase-9 on Oxidative Stress, Inflammation and Cytotoxicity in Neutrophils from Patients with Sickle Cell Anaemia. [electronic resource] - Basic & clinical pharmacology & toxicology Apr 2016 - 271-8 p. digital

Publication Type: Journal Article

1742-7843

10.1111/bcpt.12487 doi


Adult
Anemia, Sickle Cell--blood
Biomarkers--metabolism
Cell Survival--drug effects
Female
Humans
Inflammation
Male
Neutrophils--drug effects
Nitric Oxide--metabolism
Oxidative Stress--drug effects
Peroxidase--immunology
Phosphodiesterase Inhibitors--pharmacology
Pyrazoles--pharmacology
Pyrimidines--pharmacology
Tumor Necrosis Factor-alpha--immunology