Curcumin-Mediated Reversal of p15 Gene Promoter Methylation: Implication in Anti-Neoplastic Action against Acute Lymphoid Leukaemia Cell Line.

Sharma, V

Curcumin-Mediated Reversal of p15 Gene Promoter Methylation: Implication in Anti-Neoplastic Action against Acute Lymphoid Leukaemia Cell Line. [electronic resource] - Folia biologica 2015 - 81-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0015-5500

10.14712/fb2015061020081 doi


Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Cell Cycle--drug effects
Cell Line, Tumor
Chromosome Breakage--drug effects
Curcumin--pharmacology
Cyclin-Dependent Kinase Inhibitor p15--biosynthesis
DNA (Cytosine-5-)-Methyltransferase 1
DNA (Cytosine-5-)-Methyltransferases--biosynthesis
DNA Methylation--drug effects
Dose-Response Relationship, Drug
Down-Regulation--drug effects
Drug Screening Assays, Antitumor
Enzyme Induction--drug effects
Gene Expression Regulation, Leukemic--drug effects
Genomic Instability--drug effects
Humans
Neoplasm Proteins--biosynthesis
Precursor Cell Lymphoblastic Leukemia-Lymphoma--pathology
Promoter Regions, Genetic--drug effects
Reactive Oxygen Species--metabolism