HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.

Hinson, John T

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. [electronic resource] - Science (New York, N.Y.) Aug 2015 - 982-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.aaa5458 doi


Adrenergic beta-Agonists--pharmacology
Cardiomyopathy, Dilated--genetics
Cells, Cultured
Connectin--chemistry
Heart Rate
Humans
Induced Pluripotent Stem Cells--physiology
Isoproterenol--pharmacology
Mutant Proteins--chemistry
Mutation, Missense
Myocardial Contraction
Myocytes, Cardiac--physiology
RNA--genetics
Sarcomeres--physiology
Sequence Analysis, RNA
Signal Transduction
Stress, Physiological