Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma.

Yu, Mi Ok

Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma. [electronic resource] - Journal of neuro-oncology Oct 2015 - 55-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-7373

10.1007/s11060-015-1889-8 doi


Acetylcysteine--pharmacology
Brain Neoplasms--pathology
Cell Line, Tumor
Enzyme Inhibitors--pharmacology
Free Radical Scavengers--pharmacology
Gene Expression Regulation, Neoplastic--drug effects
Glioblastoma--pathology
Humans
Hypoxia--metabolism
NADPH Oxidase 4
NADPH Oxidases--genetics
Neovascularization, Pathologic--etiology
RNA, Messenger--metabolism
RNA, Small Interfering--pharmacology
Reactive Oxygen Species--metabolism
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Vascular Endothelial Growth Factor A--metabolism