Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs.

Chiu, Feng-Lan

Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs. [electronic resource] - Human molecular genetics Nov 2015 - 6066-79 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddv318 doi


Adult
Apoptosis
Caspase 3--metabolism
Cell Line
Cells, Cultured
Cyclic AMP-Dependent Protein Kinases--metabolism
DNA Damage
Dopamine and cAMP-Regulated Phosphoprotein 32--biosynthesis
Female
GABAergic Neurons--metabolism
Humans
Huntingtin Protein
Huntington Disease--genetics
Hydrogen Peroxide
Infant, Newborn
Male
Middle Aged
Nerve Degeneration
Nerve Tissue Proteins--genetics
Neurogenesis--genetics
Pluripotent Stem Cells--metabolism
Receptor, Adenosine A2A--metabolism
Young Adult