Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway.

Fu, Zhongping

Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway. [electronic resource] - Oncotarget Aug 2015 - 19469-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.3625 doi


Angiogenesis Inhibitors--pharmacology
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Curcumin--pharmacology
Dose-Response Relationship, Drug
Female
Fibrosarcoma--blood supply
Hematopoiesis--drug effects
Human Umbilical Vein Endothelial Cells--drug effects
Humans
Mice
Mice, Inbred C57BL
Neovascularization, Pathologic
Signal Transduction--drug effects
Swine
Time Factors
Vascular Endothelial Growth Factor A--antagonists & inhibitors
Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors