TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Ling, Jonathan P

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. [electronic resource] - Science (New York, N.Y.) Aug 2015 - 650-5 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.aab0983 doi


Amyotrophic Lateral Sclerosis--genetics
Animals
Autophagy-Related Proteins
Base Sequence
Cells, Cultured
Cysteine Endopeptidases--genetics
DNA-Binding Proteins--genetics
Embryonic Stem Cells
Exons--genetics
Frontotemporal Dementia--genetics
Gene Knockout Techniques
HeLa Cells
Humans
Mice
Molecular Sequence Data
Protein Isoforms--genetics
RNA Splicing
RNA Stability
RNA, Messenger--metabolism
Sequence Analysis, DNA