Discovery of highly potent, lung-localized epithelial sodium channel inhibitors.

Kumar, Manoj

Discovery of highly potent, lung-localized epithelial sodium channel inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Nov 2015 - 4797-4801 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2015.07.015 doi


Animals
Dose-Response Relationship, Drug
Drug Discovery
Epithelial Sodium Channel Blockers--adverse effects
Epithelial Sodium Channels--metabolism
Guanidines--adverse effects
Guinea Pigs
Kidney--drug effects
Lung--drug effects
Molecular Structure
Structure-Activity Relationship