A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy.

Chaudhary, Ajay K

A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy. [electronic resource] - Drug discovery today Jan 2016 - 38-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

1878-5832

10.1016/j.drudis.2015.07.014 doi


Animals
Apoptosis--physiology
Cell Membrane Permeability--physiology
Cytochromes c--metabolism
Humans
Mitochondria--metabolism
Mitochondrial Membranes--metabolism
Neoplasms--metabolism
Signal Transduction--physiology
X-Linked Inhibitor of Apoptosis Protein--metabolism