Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma.

Bhatt, Shruti

Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma. [electronic resource] - Blood Sep 2015 - 1555-64 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2015-01-624585 doi


Animals
Apoptosis--drug effects
CD4-Positive T-Lymphocytes--immunology
Cell Line, Tumor
Female
Humans
Immunologic Factors--immunology
Immunotherapy
Interleukins--immunology
Killer Cells, Natural--immunology
Lymphoma, Mantle-Cell--immunology
Mice, Inbred C57BL
Proto-Oncogene Proteins c-myc--immunology
Receptors, Interleukin-21--immunology
STAT3 Transcription Factor--immunology
Signal Transduction--drug effects
bcl-2-Associated X Protein--immunology
Interleukin-21