Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain.

Tyler, Christina R

Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. [electronic resource] - Toxicology and applied pharmacology Oct 2015 - 40-51 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1096-0333

10.1016/j.taap.2015.07.013 doi


Acetylation
Age Factors
Animals
Animals, Newborn
Arsenates--toxicity
Chromatin Assembly and Disassembly--drug effects
DNA-Binding Proteins--metabolism
Dealkylation
Dentate Gyrus--drug effects
Epigenesis, Genetic
Female
Frontal Lobe--drug effects
Gene Expression Regulation
Gestational Age
Histone Deacetylase 1--metabolism
Histone Deacetylase 2--metabolism
Histone-Lysine N-Methyltransferase--metabolism
Histones--metabolism
Jumonji Domain-Containing Histone Demethylases--metabolism
Male
Methylation
Mice, Inbred C57BL
Myeloid-Lymphoid Leukemia Protein--metabolism
Pregnancy
Prenatal Exposure Delayed Effects
Sex Factors
Water Pollutants, Chemical--toxicity
p300-CBP Transcription Factors--metabolism