The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia.

Stumpel, Dominique J P M

The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia. [electronic resource] - European journal of cancer (Oxford, England : 1990) Sep 2015 - 2008-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0852

10.1016/j.ejca.2015.06.117 doi


Acid Anhydride Hydrolases--genetics
Adenine Nucleotides--pharmacology
Antimetabolites, Antineoplastic--pharmacology
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Arabinonucleosides--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Clofarabine
Cytarabine--pharmacology
DNA Methylation
Dose-Response Relationship, Drug
Drug Synergism
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Gene Rearrangement
Histone-Lysine N-Methyltransferase--genetics
Humans
Infant
Inhibitory Concentration 50
Myeloid-Lymphoid Leukemia Protein--genetics
Neoplasm Proteins--genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma--diagnosis
Promoter Regions, Genetic
Tumor Cells, Cultured