Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

Hacke, Moritz

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol. [electronic resource] - Nature communications Jul 2015 - 7688 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-1723

10.1038/ncomms8688 doi


Animals
Anticholesteremic Agents--pharmacology
COS Cells
Cell Adhesion--drug effects
Cell Membrane--drug effects
Chlorocebus aethiops
Cholesterol--metabolism
Cytochalasin B--pharmacology
Ebolavirus--drug effects
Flow Cytometry
HEK293 Cells
HeLa Cells
Human Umbilical Vein Endothelial Cells
Humans
Microscopy, Confocal
Protein Structure, Tertiary
Simvastatin--pharmacology
Viral Fusion Proteins--drug effects
Virulence Factors--metabolism
beta-Cyclodextrins--pharmacology