IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome.

Rabeony, Hanitriniaina

IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome. [electronic resource] - European journal of immunology Oct 2015 - 2847-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-4141

10.1002/eji.201445215 doi


Adjuvants, Immunologic--adverse effects
Aminoquinolines--adverse effects
Animals
Carrier Proteins--genetics
Cytokines--genetics
Drug Eruptions--genetics
Imiquimod
Inflammasomes--genetics
Membrane Glycoproteins--genetics
Mice
Mice, Knockout
Myeloid Differentiation Factor 88--genetics
NLR Family, Pyrin Domain-Containing 3 Protein
Receptors, Interleukin-1 Type I--genetics
Signal Transduction--drug effects
Skin--immunology
Toll-Like Receptor 7--genetics