Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression.

Hunsberger, Holly C

Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression. [electronic resource] - Journal of neurochemistry Oct 2015 - 381-94 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1471-4159

10.1111/jnc.13230 doi


Alzheimer Disease--prevention & control
Animals
Brain Chemistry--drug effects
Cognition Disorders--prevention & control
Excitatory Amino Acid Antagonists--pharmacology
Glutamic Acid--metabolism
Humans
Maze Learning--drug effects
Mice
Mice, Transgenic
Neuroprotective Agents--pharmacology
Riluzole--pharmacology
Synapses--drug effects
Tauopathies--prevention & control
Vesicular Glutamate Transport Protein 1--metabolism
tau Proteins--biosynthesis