Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.

Chu, Jin

Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence. [electronic resource] - Scientific reports Jun 2015 - 11086 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

2045-2322

10.1038/srep11086 doi


Alzheimer Disease--genetics
Amyloid Precursor Protein Secretases--genetics
Amyloid beta-Peptides--genetics
Animals
Arachidonate 5-Lipoxygenase--genetics
Caspase 3--genetics
Cell Line
Disease Models, Animal
Gene Expression Regulation
Humans
Lipoxygenase Inhibitors--pharmacology
Mice
Mice, Transgenic
Neurons--metabolism
Proteins--genetics
Proteolysis
Recombinant Proteins--genetics
Signal Transduction
Transfection
Transgenes