The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL.

Lancki, D W

The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jan 1989 - 416-24 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-1767


Animals
Antibodies, Monoclonal--physiology
Antigens, Differentiation, T-Lymphocyte--immunology
Clone Cells--classification
Cyclosporins--pharmacology
Cytotoxicity Tests, Immunologic
Cytotoxicity, Immunologic--drug effects
Drug Combinations
Ethers--pharmacology
Exocytosis--drug effects
Granzymes
Interferon-gamma--antagonists & inhibitors
Ionomycin
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Phenotype
Receptors, Antigen, T-Cell--drug effects
Serine Endopeptidases--metabolism
Serine Proteinase Inhibitors
T-Lymphocytes, Cytotoxic--classification
Tetradecanoylphorbol Acetate--pharmacology