Understanding the molecular mechanism of host-based statin resistance in hepatitis C virus replicon containing cells.

Delang, Leen

Understanding the molecular mechanism of host-based statin resistance in hepatitis C virus replicon containing cells. [electronic resource] - Biochemical pharmacology Aug 2015 - 190-201 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2968

10.1016/j.bcp.2015.06.003 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--agonists
Anticholesteremic Agents--pharmacology
Antiviral Agents--pharmacology
Carbamates
Cell Line, Tumor
Drug Resistance, Viral
Enzyme Activation
Fatty Acids, Monounsaturated--pharmacology
Fluvastatin
Gene Expression Regulation
Hepacivirus--drug effects
Hepatocytes--drug effects
Host-Pathogen Interactions
Humans
Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent--genetics
Imidazoles--pharmacology
Indoles--pharmacology
Oligopeptides--pharmacology
Pyrrolidines
Replicon
Signal Transduction
Valine--analogs & derivatives
Viral Proteins--antagonists & inhibitors
Virus Replication--drug effects