The design, synthesis, and biological evaluation of novel YC-1 derivatives as potent anti-hepatic fibrosis agents.

Xiao, Juan

The design, synthesis, and biological evaluation of novel YC-1 derivatives as potent anti-hepatic fibrosis agents. [electronic resource] - Organic & biomolecular chemistry Jul 2015 - 7257-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1477-0539

10.1039/c5ob00710k doi


Actins--metabolism
Apoptosis--drug effects
Caspase 3--metabolism
Cell Line
Cell Survival
Chemistry Techniques, Synthetic
Drug Design
Gene Expression Regulation, Enzymologic--drug effects
Humans
Indazoles--chemical synthesis
Liver Cirrhosis--drug therapy
Structure-Activity Relationship