Neuroprotective effect of fasudil on inflammation through PI3K/Akt and Wnt/β-catenin dependent pathways in a mice model of Parkinson's disease.
Zhao, Yongfei
Neuroprotective effect of fasudil on inflammation through PI3K/Akt and Wnt/β-catenin dependent pathways in a mice model of Parkinson's disease. [electronic resource] - International journal of clinical and experimental pathology 2015 - 2354-64 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1936-2625
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine--analogs & derivatives
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Animals
Anti-Inflammatory Agents--pharmacology
Behavior, Animal--drug effects
Brain--drug effects
Cell Survival--drug effects
Class I Phosphatidylinositol 3-Kinases--metabolism
Cytokines--metabolism
Disease Models, Animal
Dopaminergic Neurons--drug effects
Enzyme Activation
Female
Frizzled Receptors--metabolism
Inflammation Mediators--metabolism
Mice, Inbred C57BL
Motor Activity--drug effects
Neuroprotective Agents--pharmacology
Parkinsonian Disorders--chemically induced
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Wnt Signaling Pathway--drug effects
Wnt1 Protein--metabolism
beta Catenin--metabolism
rho-Associated Kinases--antagonists & inhibitors
Neuroprotective effect of fasudil on inflammation through PI3K/Akt and Wnt/β-catenin dependent pathways in a mice model of Parkinson's disease. [electronic resource] - International journal of clinical and experimental pathology 2015 - 2354-64 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1936-2625
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine--analogs & derivatives
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Animals
Anti-Inflammatory Agents--pharmacology
Behavior, Animal--drug effects
Brain--drug effects
Cell Survival--drug effects
Class I Phosphatidylinositol 3-Kinases--metabolism
Cytokines--metabolism
Disease Models, Animal
Dopaminergic Neurons--drug effects
Enzyme Activation
Female
Frizzled Receptors--metabolism
Inflammation Mediators--metabolism
Mice, Inbred C57BL
Motor Activity--drug effects
Neuroprotective Agents--pharmacology
Parkinsonian Disorders--chemically induced
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Wnt Signaling Pathway--drug effects
Wnt1 Protein--metabolism
beta Catenin--metabolism
rho-Associated Kinases--antagonists & inhibitors