A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195.

Eigl, B J

A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195. [electronic resource] - Investigational new drugs Aug 2015 - 969-76 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

1573-0646

10.1007/s10637-015-0252-4 doi


Aged
Aged, 80 and over
Antineoplastic Agents--adverse effects
Benzimidazoles--adverse effects
Disease-Free Survival
Histone Deacetylase Inhibitors--adverse effects
Humans
Kallikreins
Male
Middle Aged
Neoplastic Cells, Circulating--metabolism
PTEN Phosphohydrolase--genetics
Prostate-Specific Antigen
Prostatic Neoplasms, Castration-Resistant--blood
Serine Endopeptidases--genetics
Trans-Activators--genetics
Transcriptional Regulator ERG