Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.

Bell, Robert J A

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. [electronic resource] - Science (New York, N.Y.) May 2015 - 1036-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1095-9203

10.1126/science.aab0015 doi


Alleles
Cell Line, Tumor
GA-Binding Protein Transcription Factor--metabolism
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Glioblastoma--genetics
Humans
Promoter Regions, Genetic
Protein Binding
Protein Multimerization
Telomerase--genetics