Activation in M1 but not M2 Macrophages Contributes to Cardiac Remodeling after Myocardial Infarction in Rats: a Critical Role of the Calcium Sensing Receptor/NRLP3 Inflammasome.

Liu, Wenxiu

Activation in M1 but not M2 Macrophages Contributes to Cardiac Remodeling after Myocardial Infarction in Rats: a Critical Role of the Calcium Sensing Receptor/NRLP3 Inflammasome. [electronic resource] - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015 - 2483-500 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1421-9778

10.1159/000374048 doi


Actins--metabolism
Animals
Carrier Proteins--metabolism
Collagen--metabolism
Down-Regulation--physiology
Extracellular Matrix--metabolism
Fibroblasts--metabolism
Fibrosis--metabolism
Heart--physiopathology
Heart Ventricles--metabolism
Inflammasomes--metabolism
Interleukin-1beta--metabolism
Macrophages--metabolism
Male
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
Myocardial Infarction--metabolism
Myocardium--metabolism
NLR Family, Pyrin Domain-Containing 3 Protein
Rats
Rats, Wistar
Receptors, Calcium-Sensing--metabolism
Signal Transduction--physiology
Tissue Inhibitor of Metalloproteinase-2--metabolism
Up-Regulation--physiology
Ventricular Remodeling--physiology