Selective spleen tyrosine kinase inhibition delays autoimmune arthritis in mice.

Zhang, Zuofu

Selective spleen tyrosine kinase inhibition delays autoimmune arthritis in mice. [electronic resource] - Molecular medicine reports Aug 2015 - 2902-6 p. digital

Publication Type: Journal Article

1791-3004

10.3892/mmr.2015.3759 doi


Animals
Ankle Joint--pathology
Arthritis, Experimental--drug therapy
Arthritis, Rheumatoid--metabolism
Cartilage--drug effects
Cells, Cultured
Collagen Type II--immunology
Cyclohexylamines--pharmacology
Cytokines--blood
Disease Models, Animal
Humans
Immunoglobulin G--blood
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Macrophages--drug effects
Male
Mice
Mice, Inbred DBA
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
Pyrimidines--pharmacology
Syk Kinase
Synovial Membrane--cytology