Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.

Devanathan, Vasudharani

Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 2015 - 6491-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1505887112 doi


Animals
Bleeding Time
Blood Platelets--metabolism
GTP-Binding Protein alpha Subunit, Gi2--deficiency
Immunoblotting
Infarction, Middle Cerebral Artery--physiopathology
Inflammation--physiopathology
Megakaryocytes--metabolism
Mice
Platelet Activation--physiology
Reperfusion Injury--physiopathology
Thrombosis--physiopathology