Clinical relevance of genetic polymorphism in CYP2C9 gene to pharmacodynamics and pharmacokinetics of phenytoin in epileptic patients: validatory pharmacogenomic approach to pharmacovigilance.

Kousar, Shazia

Clinical relevance of genetic polymorphism in CYP2C9 gene to pharmacodynamics and pharmacokinetics of phenytoin in epileptic patients: validatory pharmacogenomic approach to pharmacovigilance. [electronic resource] - International journal of clinical pharmacology and therapeutics Jul 2015 - 504-16 p. digital

Publication Type: Journal Article; Validation Study

0946-1965

10.5414/CP202112 doi


Anticonvulsants--adverse effects
Area Under Curve
Biotransformation
Case-Control Studies
Cytochrome P-450 CYP2C9--genetics
Epilepsy--drug therapy
Gene Frequency
Genotype
Humans
India
Metabolic Clearance Rate
Pharmacogenetics
Pharmacovigilance
Phenotype
Phenytoin--adverse effects
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length