The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.

Vicuña, Lucas

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. [electronic resource] - Nature medicine May 2015 - 518-23 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1546-170X

10.1038/nm.3852 doi


Acute-Phase Proteins--metabolism
Animals
Cell Separation
Dependovirus--genetics
Enzyme Inhibitors--pharmacology
Female
Ganglia, Spinal--metabolism
Hyperalgesia--physiopathology
In Situ Hybridization
Leukocyte Elastase--antagonists & inhibitors
Male
Mice
Mice, Transgenic
Neuralgia
Neurons--metabolism
Oligonucleotide Array Sequence Analysis
Pain--physiopathology
Phenotype
Polymerase Chain Reaction
Rats
Serpins--metabolism
T-Lymphocytes--cytology
Up-Regulation