The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development.
Kang, Xunlei
The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. [electronic resource] - Nature cell biology May 2015 - 665-77 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1476-4679
10.1038/ncb3158 doi
Adult
Aged
Amino Acid Motifs
Animals
Calcium-Calmodulin-Dependent Protein Kinase Type 1--genetics
Cell Line, Tumor
Cell Proliferation
Cell Survival
Cyclic AMP Response Element-Binding Protein--genetics
Female
Humans
Leukemia, Myeloid, Acute--genetics
Male
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Neoplastic Stem Cells--metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics
RNA Interference
Receptors, Immunologic--deficiency
Signal Transduction
Time Factors
Transfection
Tumor Cells, Cultured
Young Adult
The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. [electronic resource] - Nature cell biology May 2015 - 665-77 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1476-4679
10.1038/ncb3158 doi
Adult
Aged
Amino Acid Motifs
Animals
Calcium-Calmodulin-Dependent Protein Kinase Type 1--genetics
Cell Line, Tumor
Cell Proliferation
Cell Survival
Cyclic AMP Response Element-Binding Protein--genetics
Female
Humans
Leukemia, Myeloid, Acute--genetics
Male
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Neoplastic Stem Cells--metabolism
Protein Tyrosine Phosphatase, Non-Receptor Type 6--genetics
RNA Interference
Receptors, Immunologic--deficiency
Signal Transduction
Time Factors
Transfection
Tumor Cells, Cultured
Young Adult