LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential.

Hong, Christopher S

LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential. [electronic resource] - Cancer biology & therapy 2015 - 821-33 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Review

1555-8576

10.1080/15384047.2015.1040961 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Bridged Bicyclo Compounds, Heterocyclic--pharmacology
Cell Cycle--drug effects
Drug Evaluation, Preclinical
Drug Resistance, Neoplasm
Enzyme Inhibitors--pharmacology
Humans
Mitosis--drug effects
Neoplasms--drug therapy
Oncogene Proteins--antagonists & inhibitors
Piperazines--pharmacology
Protein Phosphatase 2--antagonists & inhibitors
Radiation-Sensitizing Agents--pharmacology
Tumor Protein, Translationally-Controlled 1
Tumor Suppressor Proteins--antagonists & inhibitors
Wnt Signaling Pathway--drug effects