Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma.

Cheng, Phil F

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma. [electronic resource] - Genome biology Feb 2015 - 42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1474-760X

10.1186/s13059-015-0594-4 doi


Aged
Animals
Cell Line, Tumor
Cell Proliferation--genetics
DNA Methylation--genetics
Epithelial-Mesenchymal Transition--genetics
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Melanoma--genetics
Mice
Middle Aged
Neoplasm Invasiveness--genetics
Neoplasm Staging
Prognosis
SOX9 Transcription Factor--biosynthesis
Signal Transduction
Skin Neoplasms--genetics
Survival Analysis