Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy.

Shah, Anu

Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy. [electronic resource] - Journal of the American Society of Nephrology : JASN Dec 2015 - 2963-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1533-3450

10.1681/ASN.2014050528 doi


Albuminuria--etiology
Animals
Antigens, Differentiation--analysis
Apoptosis--drug effects
Carrier Proteins--genetics
Cells, Cultured
Collagen Type IV--analysis
Creatinine--blood
Cystatin C--blood
Diabetes Mellitus, Experimental--chemically induced
Diabetic Nephropathies--metabolism
Fibrosis
Glomerular Basement Membrane--pathology
Glucose--pharmacology
Interleukin-1beta--genetics
Kidney Glomerulus--chemistry
Membrane Proteins--analysis
Mice
Mice, Knockout
Mitochondria--drug effects
NADPH Oxidase 4
NADPH Oxidases--genetics
Oxidative Stress
Oxygen--metabolism
Podocytes--chemistry
RNA, Messenger--analysis
Repressor Proteins--analysis
Streptozocin
Thioredoxins--genetics
Transforming Growth Factor beta1--analysis
WT1 Proteins