The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus.

Cayir, A

The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus. [electronic resource] - Journal of endocrinological investigation Sep 2015 - 987-98 p. digital

Publication Type: Journal Article

1720-8386

10.1007/s40618-015-0282-y doi


Acute Lung Injury--drug therapy
Animals
Bosentan
Diabetes Mellitus, Experimental--complications
Endothelin Receptor Antagonists--pharmacology
Glutathione--metabolism
Lung--drug effects
Male
Malondialdehyde--metabolism
Oxidative Stress--drug effects
Rats
Rats, Wistar
Sulfonamides--pharmacology
Superoxide Dismutase--metabolism
Transforming Growth Factor beta--metabolism
Tumor Necrosis Factor-alpha--metabolism