PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.

Teo, Adrian Kee Keong

PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells. [electronic resource] - Stem cell reports Apr 2015 - 578-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2213-6711

10.1016/j.stemcr.2015.02.015 doi


Binding Sites
Biomarkers
Cell Differentiation--genetics
Cell Line
Cluster Analysis
Computational Biology
Gene Expression Profiling
Gene Expression Regulation
Homeodomain Proteins--metabolism
Human Embryonic Stem Cells--cytology
Humans
Liver--metabolism
Nucleotide Motifs
Organ Specificity--genetics
Organogenesis--genetics
Pancreas--cytology
Position-Specific Scoring Matrices
Protein Binding
Response Elements
Trans-Activators--metabolism
Transcription, Genetic