Low dose nicotine attenuates Aβ neurotoxicity through activation early growth response gene 1 pathway.
Xue, Maoqiang
Low dose nicotine attenuates Aβ neurotoxicity through activation early growth response gene 1 pathway. [electronic resource] - PloS one 2015 - e0120267 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0120267 doi
Alzheimer Disease--metabolism
Amyloid beta-Peptides--metabolism
Animals
Apoptosis--drug effects
Blotting, Western
Cell Proliferation--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Early Growth Response Protein 1--genetics
Fluorescent Antibody Technique
Gene Expression Regulation--drug effects
Hippocampus--cytology
Humans
Immunoenzyme Techniques
Male
Mice, Inbred C57BL
Neuroblastoma--metabolism
Neurons--cytology
Nicotine--pharmacology
PC12 Cells
RNA, Messenger--genetics
Rats
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Low dose nicotine attenuates Aβ neurotoxicity through activation early growth response gene 1 pathway. [electronic resource] - PloS one 2015 - e0120267 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0120267 doi
Alzheimer Disease--metabolism
Amyloid beta-Peptides--metabolism
Animals
Apoptosis--drug effects
Blotting, Western
Cell Proliferation--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Early Growth Response Protein 1--genetics
Fluorescent Antibody Technique
Gene Expression Regulation--drug effects
Hippocampus--cytology
Humans
Immunoenzyme Techniques
Male
Mice, Inbred C57BL
Neuroblastoma--metabolism
Neurons--cytology
Nicotine--pharmacology
PC12 Cells
RNA, Messenger--genetics
Rats
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects