Synthesis of N-methylarylnitrones derived from alkyloxybenzaldehydes and antineoplastic effect on human cancer cell lines.

Costa, Débora S S

Synthesis of N-methylarylnitrones derived from alkyloxybenzaldehydes and antineoplastic effect on human cancer cell lines. [electronic resource] - Bioorganic & medicinal chemistry May 2015 - 2053-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3391

10.1016/j.bmc.2015.03.014 doi


Animals
Antineoplastic Agents--chemical synthesis
Apoptosis--drug effects
Benzaldehydes--chemistry
Cell Cycle--drug effects
Cell Line
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
K562 Cells
Mice
Molecular Structure
NIH 3T3 Cells
Nitric Oxide--antagonists & inhibitors
Nitrogen Oxides--chemical synthesis
Structure-Activity Relationship