Nerve Growth Factor Improves Survival and Function of Transplanted Islets Via TrkA-mediated β Cell Proliferation and Revascularization.

Hata, Tatsuo

Nerve Growth Factor Improves Survival and Function of Transplanted Islets Via TrkA-mediated β Cell Proliferation and Revascularization. [electronic resource] - Transplantation Jun 2015 - 1132-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1534-6080

10.1097/TP.0000000000000655 doi


Animals
Blood Glucose--metabolism
Carbazoles--pharmacology
Cell Proliferation--drug effects
Cell Survival--drug effects
Cytokines--biosynthesis
Diabetes Mellitus, Experimental--physiopathology
Graft Survival--drug effects
Indole Alkaloids--pharmacology
Inflammation Mediators--metabolism
Insulin--metabolism
Insulin Secretion
Insulin-Secreting Cells--cytology
Islets of Langerhans Transplantation--methods
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Neovascularization, Physiologic--drug effects
Nerve Growth Factor--pharmacology
Protein Kinase Inhibitors--pharmacology
Receptor, trkA--antagonists & inhibitors
Signal Transduction--drug effects
Vascular Endothelial Growth Factor A--genetics