Inhibition of receptor-interacting protein 3 upregulation and nuclear translocation involved in Necrostatin-1 protection against hippocampal neuronal programmed necrosis induced by ischemia/reperfusion injury.

Yin, Bo

Inhibition of receptor-interacting protein 3 upregulation and nuclear translocation involved in Necrostatin-1 protection against hippocampal neuronal programmed necrosis induced by ischemia/reperfusion injury. [electronic resource] - Brain research Jun 2015 - 63-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-6240

10.1016/j.brainres.2015.03.024 doi


Animals
Brain Ischemia--drug therapy
CA1 Region, Hippocampal--drug effects
Cathepsin B--metabolism
Cell Death--drug effects
Cytoplasm--drug effects
Dose-Response Relationship, Drug
Imidazoles--pharmacology
Indoles--pharmacology
Lysosomes--drug effects
Male
Necrosis--drug therapy
Neurons--drug effects
Neuroprotective Agents--pharmacology
Poly (ADP-Ribose) Polymerase-1
Poly(ADP-ribose) Polymerases--metabolism
Protein Serine-Threonine Kinases--metabolism
Rats, Sprague-Dawley
Receptor-Interacting Protein Serine-Threonine Kinases--metabolism
Reperfusion Injury--drug therapy
Up-Regulation--drug effects