Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition.

Lemoine, Sandrine

Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition. [electronic resource] - Transplantation Apr 2015 - 717-23 p. digital

Publication Type: Comparative Study; Journal Article

1534-6080

10.1097/TP.0000000000000530 doi


Animals
Apoptosis--drug effects
Biomarkers--blood
Creatinine--blood
Cyclosporine--administration & dosage
Cytoprotection
Immunosuppressive Agents--administration & dosage
Ischemic Postconditioning--methods
Kidney--drug effects
Kidney Transplantation--adverse effects
Male
Mice, Inbred BALB C
Mitochondria--drug effects
Mitochondrial Membrane Transport Proteins--antagonists & inhibitors
Mitochondrial Permeability Transition Pore
Models, Animal
Nephrectomy
Oxidative Phosphorylation--drug effects
Reperfusion Injury--metabolism
Time Factors
Urea--blood