Structural and functional characterization of a specific antidote for ticagrelor.

Buchanan, Andrew

Structural and functional characterization of a specific antidote for ticagrelor. [electronic resource] - Blood May 2015 - 3484-90 p. digital

Publication Type: Journal Article

1528-0020

10.1182/blood-2015-01-622928 doi


Adenosine--analogs & derivatives
Animals
Antibodies--isolation & purification
Antibodies, Neutralizing--chemistry
Antibody Specificity
Antidotes--chemistry
Broadly Neutralizing Antibodies
CHO Cells
Cricetinae
Cricetulus
Crystallography, X-Ray
Hemorrhage--prevention & control
Humans
Immunoglobulin Fab Fragments--pharmacology
Mice
Models, Molecular
Platelet Aggregation--drug effects
Protein Engineering
Ticagrelor