Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate.

Jabeen, S

Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate. [electronic resource] - The pharmacogenomics journal Oct 2015 - 385-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1473-1150

10.1038/tpj.2015.11 doi


Alleles
Disease-Free Survival
Dose-Response Relationship, Drug
Female
Humans
Kaplan-Meier Estimate
Male
Methotrexate--administration & dosage
Methylenetetrahydrofolate Reductase (NADPH2)--genetics
Osteosarcoma--drug therapy
Polymorphism, Single Nucleotide
Replication Protein C--genetics
Tetrahydrofolate Dehydrogenase--genetics