Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway.
Ji, Lei
Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway. [electronic resource] - The Journal of biological chemistry May 2015 - 11729-40 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M115.639351 doi
Animals
Cell Line, Tumor
Cell Movement
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms--pathology
Mice
Mutant Proteins--genetics
Mutation
Signal Transduction
Smad2 Protein--metabolism
Smad3 Protein--metabolism
Snail Family Transcription Factors
Transcription Factors--metabolism
Transcription, Genetic
Transforming Growth Factor beta--metabolism
Tumor Suppressor Protein p53--genetics
Mutant p53 promotes tumor cell malignancy by both positive and negative regulation of the transforming growth factor β (TGF-β) pathway. [electronic resource] - The Journal of biological chemistry May 2015 - 11729-40 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M115.639351 doi
Animals
Cell Line, Tumor
Cell Movement
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms--pathology
Mice
Mutant Proteins--genetics
Mutation
Signal Transduction
Smad2 Protein--metabolism
Smad3 Protein--metabolism
Snail Family Transcription Factors
Transcription Factors--metabolism
Transcription, Genetic
Transforming Growth Factor beta--metabolism
Tumor Suppressor Protein p53--genetics